Grant Permissions to Folders and Assemblies

The following procedures grant full trust permissions to an assembly or folder in a Visual Studio Tools for Office solution. Normally, you grant permissions to a specific assembly. If you have several assemblies, and you are certain that the location is secure, you can grant full trust to the folder where the assemblies are located. If you grant trust to the folder, all the assemblies in that folder and its subfolders are also trusted.

http://msdn2.microsoft.com/en-us/library/zdc263t0(VS.80).aspx